Genetic Instabilities in (CTG·CAG) Repeats Occur by Recombination

Editorial: Could Speciation Across Evolution be Governed by Genetic Switch Codes at Short Tandem Repeats?

Do simple sequence repeats in replication, repair and recombination genes of mycoplasmas provide genetic variability?

Simple sequence repeats (SSRs) or microsatellites are mono to hexa-nucleotide tandem repeats of DNA that are ubiquitous in intergenic regions and coding regions of genomes. SSRs may be essential for any genome as these repeats are found even in organisms like mycoplasmas (class Mollicutes) that have small genome size. Mollicutes cause different diseases in vertebrates including humans, insects ...

Genetic recombination in Micromonospora.

Biochemical mutants were obtained from Micromonospora chalcea, M. purpurea, and M. echinospora by using ultraviolet radiation or nitrosoguanidine. Crosses carried out between complementary nutritional mutants of the same species showed positive genetic interaction. Data are reported which indicate that the interaction between the crossed strains is due to genetic recombination. No evidence for ...

Genetic recombination in plants.

Meiotic recombination generates novel allelic arrays on chromosomes. Recent experiments have revealed an extraordinarily nonrandom distribution of recombination breakpoints along the lengths of plant chromosomes; for example, recombination breakpoints often resolve within genic sequences, and thereby generate novel alleles. The mechanism by which recombination breakpoints are determined is an a...

Genetic recombination in mycobacteria.

Evidence for genetic recombination between Mycobacterium smegmatis strain Rabinowitchi (Rab) and strain Jucho or PM5 is presented. Backcrosses of recombinants by either parental strain indicated four different types of mating behavior, suggesting that the mycobacterial compatibilities are controlled by at least two different factors. No sex factor that transfers at a high frequency or that is s...